Response after treatment with SIR-Spheres® Y-90 resin microspheres may be evaluated by CT, MRI, PET and/or changes in tumour markers.
Anatomical criteria (Response Evaluation Criteria In Solid Tumours - RECIST) can be misleading and may lead to an underestimation of the pathological tumour response, especially if determined early (<3 months). Imaging evaluation that incorporated necrosis indicators reported that response to treatment can become apparent earlier (one month).1
1. Keppke et al. Am J Roentgenol 2007; 188: 768-775.
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Effective May 7, 2021, SIR-Spheres will have the following indication for use:
SIR-Spheres Y-90 resin microspheres are indicated for the treatment of unresectable hepatocellular carcinoma (HCC) and
unresectable metastatic liver tumors from primary colorectal cancer in patients refractory to or intolerant of chemotherapy.
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