A localização primária do tumor foi capturada prospectivamente para 739 pacientes nos estudos SIRFLOX e FOXFIRE Global:

  • Tumores primários do lado direito (RSP) foram definidos como qualquer tumor primário proximal à flexão esplênica
  • Os tumores primários do lado esquerdo (LSP) incluíram qualquer tumor primário na flexura esplênica, no cólon mais distal ou no reto

Os dados de sobrevida global e sobrevida livre de progressão foram examinados independentemente para pacientes com RSP e LSP.

A resposta tumoral foi determinada de acordo com os Critérios de Avaliação de Resposta em Tumores Sólidos (RECIST) versão 1.0.

Todas as análises foram realizadas na população com intenção de tratar.

 

Gibbs P et al.  Clin Col Cancer 2018 Jun 12 ePub: doi: 10.1016/j.clcc.2018.06.001.


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