A tabela abaixo indica as características dos pacientes incluídos na Análise Combinada FOXFIRE. Não houve diferenças significativas nas características iniciais do paciente. A maioria dos pacientes apresentava fatores prognósticos ruins no início do estudo: quase 90% dos pacientes tinham doença síncrona, mais da metade dos pacientes apresentava tumor primário in situ e mais de um terço dos pacientes apresentava metástases extra-hepáticas.

*Agentes biológicos: Bevacizumab em SIRFLOX e FOXFIRE Global. Bevacizumab ou cetuximab em FOXFIRE. Biológicos.

Wasan HS et al. Lancet Oncol 2017; 18: 1159-71.


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