Os questionários de Qualidade de Vida (QV) baseados na sub-pontuação Global Health Status do EORTC QLQ-C30 foram preenchidos pelos participantes da SARAH no início e em intervalos de três meses após o tratamento inicial.

Os resultados ressaltaram o benefício das microesferas de resina SIR-Spheres® Y-90 na qualidade de vida dos pacientes. Na população com intenção de tratar (ITT), a QV foi significativamente melhor para pacientes que receberam SIRT em comparação com aqueles que receberam sorafenibe.

Os resultados do questionário QLQ-HCC 18 específico para o HCC serão publicados separadamente.

Reimpresso da The Lancet Oncology, vol. 18, Vilgrain V, Pereira H., Assenat E et al. Eficácia e segurança da radioterapia interna seletiva com microesferas de resina de ítrio-90 comparada ao sorafenibe em carcinoma hepatocelular localmente avançado e inoperável (SARAH): um estudo de fase 3 controlado randomizado, aberto, Páginas 1624-1636., Copyright (2017), com permissão de Elsevier.

Vilgrain V et al.  Lancet Oncol 2017; 18: 1624–36.




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