Recently published international recommendations for use of SIR-Spheres®

  • Newest publication of its kind focused on Dosimetry
  • Fills a major information gap across international clinical communities
  • Support best practices to treat patients collaboratively in a program-based system to improve patient outcomes
  • Developed by 43 international and multidisciplinary experts, including 23 members of the steering committee

The SIR-Spheres Advantage empowers practitioners by providing programs and tools to implement these consensus recommendations


Recommendation 23: "For selective ablative treatments, its is recommended to consider a higher specific activity, hence a lower number of microspheres." (Strong consensus)

Recommendation 17: "SIRT should be conducted as soon as possible after the simulation [...]" (Strong consensus)

Recommendation 46: "Post-SIRT dosimetry is recommended" (Strong consensus) / R21-22: "A personlized approach, using dosimetry (partition model and/or voxel-based) is recommended for activity prescription" (Strong consensus)


Levillain, H., Bagni, O., Deroose, C.M. et al. International recommendations for personalized selective internal radiation therapy of primary and metastatic liver diseases with yttrium-90 resin microspheres. Eur J Nucl Med Mol Imaging 2021; 48(5): 1570-1584.

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