Almost all treatments and drugs produce potentially unwanted side effects. Most side effects following a SIRT procedure are minor, making patients feel uncomfortable, but a small number can be serious. Every patient is different in how he or she reacts to a treatment. Many patients experience abdominal pain or tightness in their abdomen, nausea and loss of appetite which normally subsides within a week after treatment. Patients may also develop a mild fever that may last for up to a week and fatigue, which may last for several weeks post-treatment. As a precaution, specific peri-procedural medications are prescribed to control these symptoms.
In rare instances, there is a possibility that microspheres may inadvertently reach other organs in the body, such as the gallbladder, stomach, intestine, or pancreas. If SIR-Spheres® Y-90 resin microspheres reach these organs, they may cause cholecystitis, gastritis, duodentitis and pancreatitis. These complications are rare, but if they do occur they may require additional medical treatment. There is also a small risk of radiation induced liver disease (RILD) between 60 and 90 days post treatment which is characterised by jaundice, ascites and elevated bilirubin levels.
For more information please see Approved Indication.